The earliest signs of liver failure would be recurring nausea, usually after a meal. Since the liver plays a significant role in the digestion of consumed lipids (fats), it is active during digestion. When the liver begins to struggle and fail, the metabolic duties it usually performs start become challenging. You might get indigestion.
As liver failure progresses, patients might even start vomiting shortly after meals and be unable to eat much more than a liquid diet. During the end stages, fluid starts to build up in the abdominal cavity, causing a painful condition called ascites.